The #1 NAD+ supplement in the U.S.³ Learn More.

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Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg
Tru Niagen® 500mg

Tru Niagen® 500mg

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Pro 500mg dose exclusive to healthcare professionals.

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Whole-body benefits

From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.

Healthy AgingBrain HealthHeart HealthMuscle HealthCellular HealthLifestyle Stress Management*‡
Healthy Aging
Healthy Aging

Replenish NAD+ daily to keep your cells energized, supported during repair, and resilient.

Brain Health
Brain Health

Support your hardworking brain cells with increased NAD+.

Heart Health
Heart Health

Supports cellular energy that your heart cells need.

Muscle Health
Muscle Health

Help fuel your muscle cells to support recovery and repair.

Cellular Health
Cellular Health

Support your 37.2 trillion cells by supporting cellular energy, metabolism, and repair.

Lifestyle Stress Management*‡
Lifestyle Stress Management*‡

Daily stressors can deplete NAD+, which can accelerate aging. Replenish NAD+ to support your health.

Backed by gold standard science, quality, and safety

Efficacy backed by peer-reviewed published research

Niagen® is supported by 40+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen®.²

Partnership with 300+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.

Backed by independent research: Over 90% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.
View studies and publications
A clinical trial published in Nature Communications 2016

Trammell et al., 2016.

A clinical trial published in PLOS One in 2017

Airhart et al., 2017.

A clinical trial published in Nature Communications in 2018

Martens et al., 2018.

A clinical trial published in The American Journal of Clinical Nutrition in 2018

Dollerup et al., 2018.

A clinical trial published in Scientific Reports in 2019

Conze et al., 2019.

A clinical trial published in The American Journal of Clinical Nutrition in 2020

Remie et al., 2020.

A clinical trial published in The American Journal of Clinical Nutrition in 2019

Elhassan et al., 2019.

A clinical trial published in The Journal of Physiology in 2021

Stocks et al., 2021.

A clinical trial published in Science Advances in 2023

Lapatto et al., 2023.

A clinical trial published in Magnetic Resonance in Medicine in 2024

Nanga et al., 2024.

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Third-party-verified for your health

We employ rigorous quality testing to support your health. Our science-backed supplements are routinely assessed by third-party testers for quality, safety, and potency.
Learn more
Alkemist Assured™ Transparency Program

Tru Niagen products are third-party tested for identity, safety, quality, and potency by Alkemist Labs. View your product’s individual test results and Alkemist Assured™ certification on our website.

View the Alkemist Assured quality and integrity of your Tru Niagen purchase here.

Verified for potency and quality

Each batch of Tru Niagen® is verified by leading third-party labs to ensure purity and potency. Built on quality, safety, and transparency, every product meets the highest standards.

Visit our Quality page to access your bottle’s certificate of analysis.

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1 These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

2 Based on registered ongoing or completed clinical trials under "nicotinamide riboside" on clinicaltrials.gov.

3 Based on the top selling dietary supplement brands by revenue per the largest U.S. ecommerce marketplace [identified through a search dated Jan. 1, 2024 – Dec. 31, 2024 using “NAD precursors”]

†Grady et al. Journal of Virology (2012) 86(15): 8259–8268

‡Based on interpolation, we would predict an approximate 82% increase in NAD+ for 500mg, after two weeks.