Cancer

Inhibition of De Novo NAD+ Synthesis by Oncogenic URI Causes Liver Tumorigenesis through DNA Damage

Authors: Krishna S. Tummala, Ana L. Gomes, Mahmut Yilmaz, Osvaldo Grana, Latifa Bakiri, Isabel Ruppen, Pilar Ximenez-Embun, Vinayata Sheshappanavar, Manuel Rodriguez-Justo, David G. Pisano, Erwin F. Wagner, and Nabil Djouder

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Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

Authors: Giovanna Sociali, Lizzia Raffaghello, Mirko Magnone1, Federica Zamporlini, Laura Emionite, Laura Sturla, Giovanna Bianchi, Tiziana Vigliarolo, Aimable Nahimana, Alessio Nencioni, Nadia Raffaelli, Santina Bruzzone

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CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells

Authors: Grozio A, Sociali G, Sturla L, Caffa I, Soncini D, Salis A, Raffaelli N, De Flora A, Nencioni A, Bruzzone S

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