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Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
Authors: Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Xavier GDS, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG
Skeletal muscle NAMPT is induced by exercise in humans
Authors: Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, Church TS, Jubrias SA, Conley KE, Smith SR
Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
Authors: Canto C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR, Auwerx J
Nuclear DNA damage signalling to mitochondria in ageing
Authors: Fang EF, Scheibye-Knudsen M, Chua KF, Mattson MP, Croteau DL, Bohr VA
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
Authors: Canto C, Menzies KJ, Auwerx J
Targeting SIRT1 to improve metabolism: all you need is NAD+?
Authors: Carles Cantó and Johan Auwerx
Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk
Authors: Trammell SA, Yu L, Redpath P, Migaud ME, Brenner C
Safety assessment of nicotinamide riboside, a form of vitamin B3
Authors: Conze DB, Crespo-Barreto J, Kruger CL
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson's disease
Authors: DC, Ivanyuk D, Baden P, Sanchez-Martinez A, De Cicco S, Yu C, Giunta I, Schwarz LK, Di Napoli G, Panagiotakopoulou V, Nestel S, Keatinge M, Pruszak J, Bandmann O, Heimrich B, Gasser T, Whitworth AJ, Deleidi M
NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion
Authors: Diani-Moore S, Shoots J, Singh R, Zuk JB, Rifkind AB
NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease
Authors: Cerutti R, Pirinen E, Lamperti C, Marchet S, Sauve AA, Li W, Leoni V, Schon EA, Dantzer F, Auwerx J, Viscomi C, Zeviani M
The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
Authors: Canto C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J
Metabolic Inflammation-Associated IL-17A Causes Non-alcoholic Steatohepatitis and Hepatocellular Carcinoma
Authors: Gomes AL, Teijeiro A, Buren S, Tummala KS, Yilmaz, M, Waisman A, Theurillat J, Perna C, Djouder N
The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions
Authors: Fehr, Anthony R., Sasha A. Singh, Catherine M. Kerr, Shin Mukai, Hideyuki Higashi, and Masanori Aikawa.
SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems
Authors: Blanco-Melo, Daniel, Benjamin Nilsson-Payant, Wen-Chun Liu, Rasmus Moeller, Maryline Panis, David Sachs, and Randy Albrecht.
A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects
Authors: Dollerup OL, Christensen B, Svart M, Schmidt MS, Sulek K, Ringgaard S, Stodkilde-Jorgensen H, Moller N, Brenner C, Treebak JT, Jessen N
Safety and Metabolism of Longterm Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Authors: Conze D, Brenner C, Kruger CL
An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers
Authors: Airhart SE, Shireman LM, Risler LJ, Anderson GD, Nagana GA, Raftery GD, Tian R, Shen DD, O'Brien KD